Biologic initiators with UC		Biologic initiators with CD
		1-year follow-up, n (%)	2-year follow-up, n (%)	1-year follow-up, n (%)	2-year follow-up, n (%)
N		4864	2692	8910	5227
Age, years	18–29	1036 (21.30)	492 (18.28)	2402 (26.96)	1334 (25.52)
	30–39	1043 (21.44)	575 (21.36)	1882 (21.12)	1088 (20.82)
	40–49	1048 (21.55)	622 (23.11)	1839 (20.64)	1132 (21.66)
	50–59	1038 (21.34)	620 (23.03)	1725 (19.36)	1064 (20.36)
	60–69	516 (10.61)	275 (10.22)	807 (9.06)	457 (8.74)
	70–79	149 (3.06)	90 (3.34)	210 (2.36)	126 (2.41)
	80+	34 (0.70)	18 (0.67)	45 (0.51)	26 (0.50)
Sex	Female	2396 (49.26)	1347 (50.04)	4947 (55.52)	2899 (55.46)
	Male	2468 (50.74)	1345 (49.96)	3963 (44.48)	2328 (44.54)
Region	Midwest	1214 (25.21)	685 (25.60)	2302 (26.12)	1402 (27.05)
	Northeast	1022 (21.22)	562 (21.00)	1820 (20.65)	1014 (19.56)
	South	1762 (36.59)	976 (36.47)	3353 (38.04)	1966 (37.92)
	West	817 (16.97)	453 (16.93)	1339 (15.19)	802 (15.47)
Charlson score	0	3662 (75.29)	2034 (75.56)	6768 (75.96)	4042 (77.33)
	1	692 (14.23)	379 (14.08)	1202 (13.49)	668 (12.78)
	2	359 (7.38)	204 (7.58)	685 (7.69)	392 (7.50)
	3	96 (1.97)	50 (1.86)	167 (1.87)	84 (1.61)
	≥4	55 (1.13)	25 (0.93)	88 (0.99)	41 (0.78)
Index date	2010	561 (11.53)	445 (16.53)	1307 (14.67)	1039 (19.88)
	2011	935 (19.22)	609 (22.62)	1983 (22.26)	1328 (25.41)
	2012	951 (19.55)	714 (26.52)	1833 (20.57)	1385 (26.50)
	2013	1022 (21.01)	679 (25.22)	1687 (18.93)	1106 (21.16)
	2014	1093 (22.47)	245 (9.10)	1670 (18.74)	369 (7.06)
	2015	302 (6.21)	–	430 (4.83)	–