Parameter	Hemophilia A			Hemophilia B
	Moderate (n = 66)	Severe (n=115)	Moderate and Severe (n=181)	Moderate (n = 28)	Severe (n = 79)	Moderate and Severe (n = 107)
General characteristics, mean (SD)
Age, y	40.77 (16.08)	40.43 (14.29)	40.55 (14.93)	40.50 (13.40)	40.58 (14.93)	40.56 (14.49)
Weight, kg	74.79 (9.71)	75.6 (9.07)	75.30 (9.29)	77.61 (11.78)	76.1 (10.12)	76.50 (10.54)
Body mass index, kg/m2	24.63 (2.65)	24.88 (2.57)	24.79 (2.60)	24.65 (2.89)	24.73 (3.36)	24.71 (3.23)
Education, n (%)
No schooling completed	2 (3.03)	NR	2 (1.10)	NR	NR	NR
No college	36 (54.55)	78 (67.83)	114 (62.98)	13 (46.43)	40 (50.63)	53 (49.53)
College or advanced degree	20 (30.30)	33 (28.70)	53 (29.28)	11 (39.29)	36 (45.57)	47 (43.93)
Other	8 (12.12)	4 (3.48)	12 (6.63)	4 (14.29)	3 (3.8)	7 (6.54)
Home circumstances, n (%)
Lives alone	13 (19.70)	18 (15.65)	31 (17.13)	6 (21.43)	8 (10.13)	14 (13.08)
Lives with family/friends	36 (54.55)	74 (64.35)	110 (60.77)	7 (25.00)	44 (55.70)	51 (47.66)
Lives with partner	8 (12.12)	19 (16.52)	27 (14.92)	8 (28.57)	21 (26.58)	29 (27.10)
Nursing home	NR	NR	NR	1 (3.57)	1 (1.27)	2 (1.87)
Don’t know/other	9 (13.64)	4 (3.48)	13 (7.18)	6 (21.43)	5 (6.33)	11 (10.28)
Employment status, n (%)
Full-time employed	25 (37.88)	41 (35.65)	66 (36.46)	12 (42.86)	37 (46.84)	49 (45.79)
Part-time employeda	8 (12.12)	27 (23.48)	35 (19.34)	3 (10.71)	9 (11.39)	12 (11.21)
Self-employed	1 (1.52)	8 (6.96)	9 (4.97)	3 (10.71)	6 (7.59)	9 (8.41)
Student	7 (10.61)	10 (8.70)	17 (9.39)	3 (10.71)	9 (11.39)	12 (11.21)
Retired	8 (12.12)	11 (9.57)	19 (10.50)	3 (10.71)	6 (7.59)	9 (8.41)
Unemployed	4 (6.06)	3 (2.61)	7 (3.87)	NR	6 (7.59)	6 (5.61)
Other	13 (19.70)	15 (13.04)	28 (15.47)	4 (14.29)	6 (7.59)	10 (9.35)
Comorbidities, n (%)
Anemia	6 (9.09)	12 (10.43)	18 (9.94)	3 (10.71)	8 (10.13)	11 (10.28)
Anxiety	19 (28.79)	26 (22.61)	45 (24.86)	1 (3.57)	16 (20.25)	17 (15.89)
Atrial fibrillation	1 (1.52)	3 (2.61)	4 (2.21)	1 (3.57)	1 (1.27)	2 (1.87)
Attention deficit disorder	NR	NR	NR	1 (3.57)	1 (1.27)	2 (1.87)
Gingivitis	5 (7.58)	5 (4.35)	10 (5.52)	1 (3.57)	5 (6.33)	6 (5.61)
Hepatitis C	3 (4.55)	8 (6.96)	11 (6.08)	1 (3.57)	1 (1.27)	2 (1.87)
HIV	1 (1.52)	6 (5.22)	7 (3.87)	NR	NR	NR
Myocardial infarction	2 (3.03)	1 (0.87)	3 (1.66)	1 (3.57)	2 (2.53)	3 (2.80)
Obesity	3 (4.55)	6 (5.22)	9 (4.97)	4 (14.29)	5 (6.33)	9 (8.41)
Osteoarthritis	10 (15.15)	16 (13.91)	26 (14.36)	3 (10.71)	6 (7.59)	9 (8.41)
Osteoporosis	5 (7.58)	10 (8.69)	15 (8.29)	NR	3 (3.80)	3 (2.80)
Stroke	NR	1 (0.87)	1 (0.55)	1 (3.57)	1 (1.27)	2 (1.87)
Type I diabetes	2 (3.03)	1 (0.87)	3 (1.66)	1 (3.57)	1 (1.27)	2 (1.87)
Type II diabetes mellitus	6 (9.09)	6 (5.22)	12 (6.63)	NR	4 (5.06)	4 (3.74)
None	21 (31.82)	50 (43.48)	71 (39.23)	12 (42.86)	36 (45.57)	48 (44.86)
Treatment strategy, n (%)
No treatment received 12 mo priorb	41 (62.12)	NR	41 (22.65)	21 (75.00)	NR	21 (19.63)
Primary prophylaxis	NR	22 (19.13)	22 (12.15)	NR	48 (60.76)	48 (44.86)
Secondary prophylaxis	NR	36 (31.30)	36 (19.89)	NR	11 (13.92)	11 (10.28)
Primary on-demand	20 (30.30)	49 (42.61)	69 (38.12)	6 (21.43)	18 (22.78)	24 (22.43)
Secondary on-demand	5 (7.58)	8 (6.96)	13 (7.18)	1 (3.57)	2 (2.53)	3 (2.80)
Treatment class, n (%)
EHL	4 (6.06)	16 (13.91)	20 (11.05)	1 (3.57)	23 (29.11)	24 (22.43)
Plasma-derived	2 (3.03)	16 (13.91)	18 (9.94)	2 (7.14)	30 (37.94)	32 (29.91)
SHL	58 (87.87)	82 (71.30)	140 (77.35)	25 (89.29)	26 (32.91%)	51 (47.66)