Metric	ETHOS-Eligible Population		Expanded ETHOS-Eligible Population
	Average (5th-⁠95th Percentile)	% of Total, Average (5th-⁠95th Percentile)	Average (5th-⁠95th Percentile)	% of Total, Average (5th-⁠95th Percentile)
Cumulative years of life extended (millions)	0.983 (0.700, 1.355)	4.8 (3.4, 6.6)	2.976 (2.564, 3.485)	5.1 (4.4, 5.9)
Severe exacerbations avoided per year per patient	0.039 (0.032, 0.046)	14.9 (12.3, 17.7)	0.042 (0.039, 0.046)	15.3 (14.1, 16.6)
Moderate exacerbations avoided per year per patient	0.159 (0.145, 0.173)	15.4 (14.0, 16.8)	0.164 (0.157, 0.172)	15.7 (14.9, 16.3)
All-cause mortality reduction, %	1.0 (0.7, 1.4)	25.5 (18.2, 35.5)	1.0 (0.9, 1.2)	20.7 (17.8, 24.3)
Years of life added per patient	2.22 (0.74, 4.08)	14.3 (4.8, 26.2)	1.72 (1.12, 2.36)	10.3 (6.7, 14.2)
No. needed to treata	8 (21, 4)	n/a	10 (15, 8)	n/a