Patients With ET Patients Without ET (n=5244)
Overall (n = 5286) Treatment Group P
Valueb
Untreated (n = 1374) Pharmacotherapy (n = 3767) Invasive Therapy (n=145) P
Valueb
All-cause HCRU
Any inpatient admission, n (%) 1111 (21.02) 230 (16.74) 845 (22.43) 36 (24.83) <.0001 864 (16.5) <.0001
Any ED visit, n (%) 1595 (30.17) 351 (25.55) 1197 (31.78) 47 (32.41) <.0001 1313 (25.04) <.0001
LOS, mean (SD) 3.31 (13.33) 2.46 (10.57) 3.64 (14.32) 2.78 (9.02) <.0001 2.68 (11.81) <.0001
All-cause HCCs ($), mean (SD)
Inpatient admissions 5645 (30 705) 4598 (46 871) 5921 (22 120) 8386 (28 965) <.0001 4168 (15 294) <.0001
ED visit 916 (2824) 680 (1855) 986 (3085) 1361 (3184) <.0001 635 (2233) <.0001
PCP visits 621 (560) 556 (520) 640 (568) 735 (633) <.0001 442 (448) <.0001
Specialist visit 1348 (4506) 961 (1336) 1449 (5226) 2371 (3325) <.0001 1049 (5237) <.0001
Total medical 13 723 (36 836) 10 823 (50 401) 14 358 (30  96) 24 726 (36 888) <.0001 10 308 (23 887) <.0001
Total pharmacyc 3837 (11 550) 2432 (7625) 4289 (12 580) 5403 (13 256) <.0001 2929 (9921) <.0001
Total allowed costsc 17 560 (39 972) 13 255 (51 528) 18 647 (34 626) 30 130 (40 011) <.0001 13 237 (27 098) <.0001
ET-related HCRU
Any inpatient admission, n (%) 374 (7.08) 84 (6.11) 276 (7.33) 14 (9.66) 0.1523 N/A
Any ED visit, n (%) 198 (3.75) 40 (2.91) 151 (4.01) 7 (4.83) 0.1462 N/A
LOS, mean (SD) 0.71 (5.14) 0.68 (4.18) 0.74 (5.54) 0.32 (01.42) <.0001 N/A
ET-related HCCs ($), mean (SD)
Inpatient admissions 1296 (9947) 1040 (5406) 1346 (11 118) 2426 (10 843) 0.1455 N/A
ED visit 122 (839) 87 (629) 133 (906) 148 (762) 0.1438 N/A
PCP visits 144 (179) 158 (175) 141 (181) 116 (184) <.0001 N/A
Specialist visit 176 (472) 154 (537) 167 (345) 614 (1451) <.0001 N/A
Total medical 2080 (10 518) 1687 (5610) 1987 (11 254) 8247 (12 217) <.0001 N/A
Total pharmacyc 153 (602) 0 (0) 189 (614) 663 (1714) <.0001 N/A
Total surgicalc 151 (3100) 0 (0) 0 (0) 5512 (17 969) <.0001 N/A
Total allowed costsc 2233 (10 544) 1687 (5610) 2176 (11 280) 8911 (20 119) <.0001 N/A
ET-related costs over total HCCs (%) 13%
(2233/17 560)
13%
(1687/13 255)
12%
(2176/18 647)
30%
(8911/30 130)
<.0001 N/A