Comorbidity Patients With ET Patients Without ET (n = 5244)
Overall (n = 5286) Treatment Group P Valuec
Untreated (n = 1374) Pharmacotherapy (n = 3767) Invasive Therapy (n = 145) P Valueb
Depression 1354 (25.61) 264 (19.21) 1035 (27.48) 55 (37.93) <.0001 801 (15.27) <.0001
Anxiety 1466 (27.73) 250 (18.2) 1159 (30.77) 57 (39.31) <.0001 810 (15.45) <.0001
Stress and adjustment disorders 278 (5.26) 54 (3.93) 214 (5.68) 10 (6.9) .0303 168 (3.2) <.0001
Dissociative and conversion disorders 31 (0.59) 6 (0.44) 24 (0.64) 1 (0.69) .6973 10 (0.19) .0011
Somatoform disorders 41 (0.78) 7 (0.51) 30 (0.8) 4 (2.76) .0129 20 (0.38) .0077
Substance use disorders 729 (13.79) 122 (8.88) 583 (15.48) 24 (16.55) <.0001 551 (10.51) <.0001
Any comorbid psychiatric conditions 2425 (45.88) 488 (35.52) 1853 (49.19) 84 (57.93) <.0001 1630 (31.08) <.0001