Apomorphine Sublingual Film	Apomorphine Hydrochloride Injection	Levodopa Inhalation Powder	Apomorphine Sublingual Film vs. Apomorphine Hydrochloride Injection	Apomorphine Sublingual Film vs. Levodopa Inhalation Powder
Scenario 1: Efficacy data from an indirect treatment comparison of apomorphine sublingual film and levodopa inhalation powdera
Total costs	$45 802	$280 139	$73 139	–$234 337	–$27 337
QALY, years	4.141	4.116	4.071	0.025	0.070
Incremental cost per QALY gained	–	–	–	Dominant	Dominant
Scenario 2: Assuming linear change in utility per “OFF” hour reduced
Total costs	$45 864	$280 212	$73 317	–$234 349	–$27 454
QALY, years	3.983	3.961	3.871	0.022	0.112
Incremental cost per QALY gained	–	–	–	Dominant	Dominant
Scenario 3: Limiting the model horizon to 5 years
Total costs	$30 918	$187 248	$48 874	–$156 330	–$17 956
QALY, years	2.731	2.702	2.578	0.029	0.153
Incremental cost per QALY gained	–	–	–	Dominant	Dominant
Scenario 4: Considering costs owing to caregiver burden
Total costs	$484 956	$716 066	$530 675	–$231 110	–$45 719
QALY, years	4.107	4.088	3.872	0.019	0.235
Incremental cost per QALY gained	–	–	–	Dominant	Dominant