Pediatric (≤6 years of age) Pediatric (>6 years of age) Adult Source
By Non-specialized Care
Monotherapy 26 996 66 662 70 833 From Prescription data*
Two-drug Therapy 45 444 92 464 100 224
Three-drug Therapy 68 014 121 571 131 913
Four-drug Therapy 94 728 157 249 168 288
By Specialized Care
Monotherapy 35 623 79 938 88 609 National Center Hospital,
National Center of Neurology and Psychiatry, Tokyo, Japan
Two-drug Therapy 53 635 103 440 116 485
Three-drug Therapy 70 018 128 743 149 759
In Seizure Reduction 85 151 140 941 150 628
In Difficult-to-treat 85 151 140 941 150 628