Variable Remestemcel-L-rknd
N=55
Ruxolitinib
N=49
ORR P-Value** ORR Final Model Rationale
Age (years) 0.98 Omitted due to difference in age inclusion
Median 7 57 criteria
Range <1-17 18-72
Sex 0.39 Included-strongly imbalanced and potential effect modifier by key aGVHD clinical experts
Male (%) 64% 47%
Ethnicity 0.81 Included-strongly imbalanced and potential effect modifier by key aGVHD clinical experts
White (%) 56% 92%
Other (%) 44% 8%
Baseline aGVHD grade (%)* 0.40 Included-strongly imbalanced and potential effect modifier by key aGVHD clinical experts
II 11% 27%
III 42% 55%
IV 47% 18%