All Patients at Follow-Up c
(N=598)
First-Line Therapy
(N=598)
Second-Line Therapy (n=180) Third-Line Therapy (n=51) Fourth-Line Therapy
(n=21)
Fifth-Line Therapy
(n=11)
Total Health Care Costs, Mean (SD)d 56 831 (55 133) 97 141 (144 730) 125 586 (278 654) 239 216 (548 666) 370 597 (718 510) 424 758 (715 028)
Medical Costs, Mean (SD)e 50 925 (49 851) 91 567 (143 091) 116 566 (277 073) 222 686 (551 657) 275 817 (671 979) 351 892 (724 222)
Inpatient Visits 5416 (13 821) 8132 (57 990) 13 347 (65 897) 11 357 (27 185) 15 331 (31 893) 17 827 (36 579)
Emergency Care 1108 (3233) 1670 (10 503) 1364 (4842) 1359 (2798) 1159 (2174) 2253 (4109)
Office Visit Costs 1627 (1180) 2125 (2483) 2005 (1692) 2763 (4031) 1950 (1300) 2537 (2311)
Outpatient Costs, Mean (SD)
Chemotherapy Drugsf 26 284 (35 463) 55 298 (106 995) 68 377 (221 547) 92 648 (147 050) 163 864 (393 490) 112 146 (169 753)
Diagnosisi 4907 (6976) 7119 (13 859) 7825 (16 858) 44 907 (277 700) 10 591 (11 851) 8220 (6878)
Medical Servicesk 4627 (5490) 8313 (17 811) 16 095 (103 286) 58 595 (337 313) 77 418 (281 538) 205 462 (626 195)
Surgery 2363 (3533) 3082 (12 118) 3131
(5929)
1849 (3145) 1800 (2468) 2787 (2819)
Otheri 4596 (13 880) 5832 (16 993) 4425 (13 764) 9209 (42 679) 3705 (7492) 659 (1571)
Total Pharmacy Costs, Mean (SD)j 5905 (15 937) 5573 (17 068) 9020 (36 518) 16 530 (41 144) 94 780 (193 984) 72 865 (128 966)
Total FL-Related Health Care Costs, Mean (SD) 13 821 (19 173) 29 557 (83 633) 29 460 (109 186) 103 387 (406 719) 309 103 (722 131) 85 748 (131 478)
FL-Related Medical Costs, Mean (SD)k 4496 (9918) 8627 (23 159) 6172 (24 872) 57 670 (327 059) 27 511 (52 680) 1850 (5215)
FL-Related Inpatient Visits 605 (4154) 924 (8826) 1871 (22 591) 5053 (22 098) 2979 (10 936) 447 (1412)
FL-Related Emergency Care Visits 32 (222) 32 (265) 14 (126) 117 (519) 0 (0) 0 (0)
FL-Related Outpatient Visits 3859 (8826) 7671 (21 416) 4288 (10 667) 52 501 (327 113) 24 532 (51 108) 1403 (3808)
FL-Related Office Visits 285 (719) 499 (1472) 332 (710) 995 (3826) 424 (918) 270 (741)
FL-Related Other Visits 3574 (8547) 7172 (20 598) 3955 (10 390) 51 506 (327 038) 24 108 (51 118) 1133 (3071)
Costs Of FL-Related Transplant Cell in Any Medical Setting 12 (194) 3 (64) 3 (40) 109 (776) 50 (230) 0 (0)
FL-Related Total Pharmacy Costs, Mean (SD)l 9325 (14 094) 20 930 (67 618) 23 288 (105 083) 45 717 (112 893) 281 593 (687 685) 83 898 (130 605)
Costs Of FL-Related Drugs in Any Medical Settingm 8534 (12 637) 19 990 (66 916) 19 521 (100 468) 36 131 (109 983) 195 616 (648 897) 14 720 (46 550)
Cost Of FL-Related Oral Drugs 791 (6490) 941 (11 381) 3767 (32 996) 9586 (36 494) 85 977 (197 500) 69 177 (130 972)