Line of Therapy	Mean (SD)	Median (IQR)
First-line therapy (n=598)	370 (467)	141 (602)
Second-line therapy (n=261)	392 (435)	259 (541)
Third-line therapy (n=72)	162 (233)	85 (123)
Fourth-line therapy (n=24)	148 (227)	42 (84)
Fifth-line therapy (n=11)	88 (151)	21 (133)