Pimobendan Prescription Group vs. Non-prescription Group (ref = Non-prescription Group)
Before Propensity Score Matching After Propensity Score Matching
All, N 10 258 552
Pimobendan prescription group, n 473 276
Non-prescription group, n 9785 276
Standardized mean difference (pimobendan prescription group–non-prescription group)
Age 0.18 0.01
Sex -0.26 0.05
Interval between hospitalizations for heart failure 0.13 0.09
ADL score at discharge -0.15 0
NYHA class 0.19 0.08
Underlying heart disease
Ischemic heart disease -0.24 0.01
Cardiomyopathy -0.39 -0.03
Valvular disease 0 0.01
Arrhythmia -0.25 0.01
Other heart diseases 0.01 0.04
Information on hospital visit that served as the baseline for start of the follow-up period
Inpatient clinical department - Cardiology department -0.07 0.08
Inpatient clinical department - Cardiovascular surgery 0.09 0
Inpatient clinical department–Others 0.04 -0.04
Discharge to home -0.08 -0.11
Duration (days) spent in hospital -0.34 0.07
Concomitant drugs and therapy receive during the hospital visit that served as the baseline for start of the follow-up period
Inotropic agents (intravenous injection) -0.56 -0.06
Diuretics (intravenous injection) -0.01 0.02
Tolvaptan -0.4 0.04
Carperitide -0.13 0.08
Concomitant drugs and therapy during follow-up
ACE-I and/or ARB 0 0.06
β blocker -0.39 -0.03
Digitalis preparation -0.16 -0.05
Diuretics (excluding tolvaptan and mineralocorticoid receptor antagonist) -0.27 0.03
Tolvaptan -0.45 -0.07
Mineralocorticoid receptor antagonist -0.28 -0.06
Statin -0.07 0.18
Nitrates -0.08 0.03
Cardiac rehabilitation -0.08 -0.04
Concomitant disease during the hospital visit that served as the baseline for start of the follow-up period
Atrial fibrillation -0.09 0.03
Diabetes (including abnormal glucose tolerance) -0.17 -0.06
Hypertension -0.23 0.13
Dyslipidemia -0.21 0.15