Recurrent and Metastatic HNC Patients		Pt-Refractory Patients
		Mean	%	Mean	%
Total N		3224		842	-
Gender	Male	2594	80.5%	687	81.6%
	Female	630	19.5%	155	18.4%
Age (year)	Mean	67.5	-	62.7	-
	SD	12.1	-	10.9	-
	Minimum	18.0	-	22.0	-
	Median	68.0	-	65.0	-
	Maximum	99.0	-	90.0	-
History of smoking	Yes	2274	70.5%	644	76.5%
	No	950	29.5%	190	22.6%
Type of cancer	Oral cavity	687	21.3%	178	21.1%
	Maxillary	406	12.6%	107	12.7%
	Oropharynx	458	14.2%	134	15.9%
	Hypopharynx	635	19.7%	234	27.8%
	Larynx	759	23.5%	165	19.6%
	Salivary gland	302	9.4%	45	5.3%
	Nasopharynx	207	6.4%	93	11.0%
Stagea	0	2	0.1%	2	0.2%
	I	47	1.5%	54	6.4%
	II	48	1.5%	120	14.3%
	III	1266	39.3%	194	23.0%
	IVA	975	30.2%	197	23.4%
	IVB	372	11.5%	115	13.7%
	IVC	514	15.9%	160	19.0%